Always ensure to auto arrange, this will ensure you don't overstack deliveries on your back and case you to lose balance. There is also a side quest which will get you a upgrade for you backpack which feel is very important.
Speaking of which, do sidequests...they will net you upgrades that will help you on your journey.
The map will show you the timefall areas and the duration, however there are some area which are always under timefall
Once you hit a certain level with a distry centre in the story,they will unlock the ability to fabricate shoes and other stuff, always keep an extra pair on your person at all times. If not, there is always Sandalweed.