Right Posted July 20, 2020 Report Share Posted July 20, 2020 2 hours ago, Bird Bird Bird said: Yup. Thank you. I have enough Amazon boxes lying around. All I need is a enough aluminium foil. Quote Link to comment Share on other sites More sharing options...
Right Posted July 20, 2020 Report Share Posted July 20, 2020 More news awaited. But oxford team cracked MERS and nearly cracked SARS, so hope is high. Quote Link to comment Share on other sites More sharing options...
Big Boss Posted July 20, 2020 Author Report Share Posted July 20, 2020 2 hours ago, Black_Hawk said: Complete Lockdown in West Bengal TWICE a week to be followed till August 31st' 2020. This week complete Lockdown on Thursday (23rd July) and Saturday (25th July). They should keep changing the days and confuse the virus, since it can attack on only 2 days of a week. What a masterstroke. 2 4 Quote Link to comment Share on other sites More sharing options...
Bhpian Bali Posted July 20, 2020 Report Share Posted July 20, 2020 Quote Link to comment Share on other sites More sharing options...
Bird Bird Bird Posted July 20, 2020 Report Share Posted July 20, 2020 (edited) 18 minutes ago, Right said: More news awaited. But oxford team cracked MERS and nearly cracked SARS, so hope is high. Much much more data needed. I'm sure most candidates, if not all, will elicit immunogenic reaction. The game is on safety and longevity. So at the very least 2021, more likely 2022. Edit: The paper is free at Lancet. Lots of data to go through though. Appendix is 100 pages+ ! Edited July 20, 2020 by Bird Bird Bird Quote Link to comment Share on other sites More sharing options...
Pushy Posted July 20, 2020 Report Share Posted July 20, 2020 16 minutes ago, Bhpian Bali said: BS! why do they want the virus to get out of the mask, and for uninfected persons, if they assume that the virus do want to get out of the mask, then what the F is it doing inside despite the mask in the first place? defeats the whole purpose of using the mask...stupid sh*t. Quote Link to comment Share on other sites More sharing options...
dylanjosh Posted July 20, 2020 Report Share Posted July 20, 2020 1 minute ago, Pushy said: BS! why do they want the virus to get out of the mask, and for uninfected persons, if they assume that the virus do want to get out of the mask, then what the F is it doing inside despite the mask in the first place? defeats the whole purpose of using the mask...stupid sh*t. take a deep breath think Quote Link to comment Share on other sites More sharing options...
Pushy Posted July 20, 2020 Report Share Posted July 20, 2020 Just now, dylanjosh said: take a deep breath think the only thing you would want to breathe out from the mask are the gases and not the viruses Quote Link to comment Share on other sites More sharing options...
dylanjosh Posted July 20, 2020 Report Share Posted July 20, 2020 They are saying the mask does not stop the virus from being breathed out so no use weaing it. whats difficult to understand? They are talking about infected people obviously. Quote Link to comment Share on other sites More sharing options...
Big Boss Posted July 20, 2020 Author Report Share Posted July 20, 2020 7 minutes ago, Pushy said: the only thing you would want to breathe out from the mask are the gases and not the viruses Respirator N95 only prevents incoming virus and not outgoing. So if you are infected patient or asymptomatic infected, you will still infect others, so complete purpose of mask is not served. Mask is there to prevent infecting others too. 1 Quote Link to comment Share on other sites More sharing options...
Right Posted July 20, 2020 Report Share Posted July 20, 2020 33 minutes ago, Bird Bird Bird said: Much much more data needed. I'm sure most candidates, if not all, will elicit immunogenic reaction. The game is on safety and longevity. So at the very least 2021, more likely 2022. Edit: The paper is free at Lancet. Lots of data to go through though. Appendix is 100 pages+ ! Yeah, I just read a little. But good progress made by the team. Whats the sample size they use to declare a vaccine safe? 10k? And how long do they wait for side-effects...to appear? Quote Link to comment Share on other sites More sharing options...
Bird Bird Bird Posted July 20, 2020 Report Share Posted July 20, 2020 (edited) 9 minutes ago, Right said: Yeah, I just read a little. But good progress made by the team. Whats the sample size they use to declare a vaccine safe? 10k? And how long do they wait for side-effects...to appear? There's no fixed number AFAIK. You've to determine the primary and secondary end points (quantify them), determine the power of the study, and then calculate sample size. This is both for safety and efficacy (P3). Ideally this trial will go for 2-3 years at least. Safety will be a part of it. Post launch, I am sure most of them will do a PMS/OR P4 for some years if not much. Very rare/unknown AEs will be caught during P4 since you'll have extremely large sample size. Or from anecdotal evidence of injectors/patients. Never conducted a vaccine trial (all experience is from drug trials), so I might be incorrect. Edited July 20, 2020 by Bird Bird Bird 1 Quote Link to comment Share on other sites More sharing options...
PhantomShade Posted July 20, 2020 Report Share Posted July 20, 2020 Pandemic impact: IndiGo to lay off 10% employees Are we going the way of Brazil and SA? It all lines up, poor, heavy inequality, nobody bothers to invest in the employment generating sectors, banks unwilling to lend, low GDP growth rate etc. Quote Link to comment Share on other sites More sharing options...
Right Posted July 20, 2020 Report Share Posted July 20, 2020 19 minutes ago, Bird Bird Bird said: There's no fixed number AFAIK. You've to determine the primary and secondary end points (quantify them), determine the power of the study, and then calculate sample size. This is both for safety and efficacy (P3). Ideally this trial will go for 2-3 years at least. Safety will be a part of it. Post launch, I am sure most of them will do a PMS/OR P4 for some years if not much. Very rare/unknown AEs will be caught during P4 since you'll have extremely large sample size. Or from anecdotal evidence of injectors/patients. Never conducted a vaccine trial (all experience is from drug trials), so I might be incorrect. Thank you. Very informative. so nothing before July-August 2021. :-/ Quote Link to comment Share on other sites More sharing options...
Right Posted July 20, 2020 Report Share Posted July 20, 2020 Karnataka gets a grip again. positive rate has gone down to 10% after hovering above 15% for last couple of weeks. Testing has been doubled within a week, from 17k to 34k. 10k increase just in last 2 days. thank you dear CM. 1 Quote Link to comment Share on other sites More sharing options...
Black_Hawk Posted July 20, 2020 Report Share Posted July 20, 2020 3 hours ago, Big Boss said: They should keep changing the days and confuse the virus, since it can attack on only 2 days of a week. What a masterstroke. Abbeh...ROFL They should have just done a 2 week Lockdown and then gone from there. The 2 days a week is a joke. Kuch nahi hogaa unless like you mentioned COVID becomes confused and decides to hightail it outta here Quote Link to comment Share on other sites More sharing options...
silica Posted July 21, 2020 Report Share Posted July 21, 2020 11 hours ago, Pushy said: BS! why do they want the virus to get out of the mask, and for uninfected persons, if they assume that the virus do want to get out of the mask, then what the F is it doing inside despite the mask in the first place? defeats the whole purpose of using the mask...stupid sh*t. They are only talking about N-95 masks which have respiratory valves; not regular N-95 masks. Quote Link to comment Share on other sites More sharing options...
Right Posted July 21, 2020 Report Share Posted July 21, 2020 Trust NOONE! 9 Quote Link to comment Share on other sites More sharing options...
Ne0 Posted July 21, 2020 Report Share Posted July 21, 2020 ^^ was that from your home ? Quote Link to comment Share on other sites More sharing options...
Right Posted July 21, 2020 Report Share Posted July 21, 2020 44 minutes ago, Ne0 said: ^^ was that from your home ? Haha. no. Quote Link to comment Share on other sites More sharing options...
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